Publications

* denotes equally contributing authors
** denotes co-corresponding authors
‡ denotes undergraduate co-authors

Pre-prints

Peer reviewed articles

Other scientific publications

Prior Publications

  • Jinsheng, D., Aitken, C.E., Lorsch, J.R., and Hinnebusch. A.G., and “Rps3/uS3 residues in the 40S ribosomal entry channel stabilize preinitiation complex assembly at initiation codons in vivo.” PNAS 2016
  • Aitken, C.E., Beznosková, P., Vlčkova, V., Chiu, W.L., Zhou, F., Valášek, L., Hinnebusch. A.G., and Lorsch, J.R. (2016) “Distinct roles for eIF3 at the pre-initiation complex entry and exit channels.” eLife 2016
  • Llácer, J.L.*, Hussain, T.*, Marler, L., Aitken, C.E., Thakur, A., Lorsch, J.R., Hinnebusch, A.G., and Ramakrishnan, V. “Conformational differences between open and closed states of the eukaryotic translation initiation complex.” Molecular Cell 2015
  • Tsai, A., Uemura, S., Johansson, M., Puglisi, E.V., Marshall, R.A., Aitken, C.E., Korlach, J., Ehrenberg, M., and Puglisi, J.D. “The impact of aminoglycosides on the dynamics of translation elongation.” Cell Reports 2013
  • Aitken, C.E., and Lorsch, J.R. “A Mechanistic Overview of Eukaryotic Translation Initiation.” Nature Structural and Molecular Biology 2012 (Invited Review)
  • Mitchell, S.F., Walker, S.E., Rajagopal, V., Aitken, C.E., and Lorsch, J.R. “Recruiting knotty partners: The roles of translation initiation factors in mRNA recruitment to the eukaryotic ribosome.” In: Ribosomes: Structure, Function and Dynamics, Springer, Heidelberg 155-170 2011 (Invited Review)
  • Lucent, D., Snow, C.D., Aitken, C.E., and Pande, V.S. “Non-bulk-like solvent behavior in the ribosome exit tunnel.” PLoS Comput Biol 2010
  • Aitken, C.E., and Puglisi, J.D. “Following the intersubunit conformation of the ribosome during translation in real time.” Nature Structural and Molecular Biology 2010
  • Uemura, S., Aitken, C.E., Korlach, J., Flusberg, B.A., Turner, S.W., and Puglisi, J.D. “Real-time tRNA transit on single translating ribosomes at codon resolution.” Nature 2010
  • Aitken, C.E., Petrov, A., and Puglisi, J.D. “Single Ribosome Dynamics and the Mechanism of Translation.” Annual Review of Biophysics 2010 (Invited Review)
  • Marshall, R.A.*, Aitken, C.E.*, and Puglisi, J.D. “GTP hydrolysis by IF2 guides progression of the ribosome into elongation.” Molecular Cell 2009
  • Aitken, C.E., Marshall, R.A., Dorywalska, M., and Puglisi, J.D. “Single Molecule Studies of Prokaryotic Translation.” Single Molecule Biology. Ed. Alex Knight. Academic Press: New York. 2009 (Book Chapter)
  • Knee, K.M., Dixit, S.B., Aitken, C.E., Ponomarev, S., Beveridge, D.L., and Mukerji, I. “Spectroscopic and molecular dynamics evidence for a sequential mechanism for the A-to-B transition in DNA.” Biophysical Journal 2008
  • Marshall, R.A., Aitken, C.E., Dorywalska, M., and Puglisi, J.D. “Translation at the single- molecule level.” Annual Review of Biochemistry. 2008. (Invited Review)
  • Aitken, C.E.*, Marshall, R.A.*, and Puglisi, J.D. “An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments.” Biophysical Journal 2007
  • McKenna, S.A, Lindhout, D.A., Aitken, C.E., Shimoike, T., and Puglisi, J.D. “Viral dsRNA inhibitors prevent self-association and autophosphorylation of PKR.” Journal of Molecular Biology 2007
  • McKenna, S.A, Kim, I., Viani Puglisi, E., Lindhout, D.A., Aitken, C.E., Marshall, R.A., and Puglisi, J.D. “Purification and characterization of transcribed RNAs using fast performance liquid chromatography.” Nature Protocols 2007
  • Lindhout, D.A., McKenna, S.A., Aitken, C.E., Liu, C.W., and Puglisi, J.D. “PKR: A NMR Perspective” Progress in Nuclear Magnetic Resonance Spectroscopy 2007 (Invited Review)
  • McKenna, S.A, Lindhout, D.A., Aitken, C.E., and Puglisi, J.D. “Molecular insights into PKR activation by viral double-stranded RNA.” Structure and Biophysics – New Technologies for current Challenges in Biology and Beyond. Chapter 8; 93-104. Springer Publishing: New York. 2007 (Book chapter)